SS-31 Elamipretide 25mg Pre Mixed

Description

SS-31 Elamipretide Pre Mixed Peptide 25mg Pen

This product is intended for research purposes only. To be used by trained professionals only.

Elamipretide, also known as SS-31, is a synthetic tetrapeptide that has shown significant promise in biomedicine. It is part of a new family of drugs that selectively target mitochondria, the powerhouses of cells, in order to restore their function. This peptide can cross cell and organelle membranes and is hypothesised to interfere with the generation of reactive oxygen species within the mitochondria, resulting in enhanced physiological function [1].

SS-31 Elamipretide pre mixed peptide has been proven in recent research to alleviate mitochondrial dysfunction, synaptic damage, and memory loss in mice produced by lipopolysaccharides [2]. This highlights the peptide’s potential as a treatment for neurodegenerative disorders including Alzheimer’s and Parkinson’s, in which mitochondrial dysfunction is a prominent pathogenic hallmark.

SS-31’s interaction with membranes and effect on surface electrostatics is one of its primary chemical mechanisms of action [3]. It binds specifically to cardiolipin, a phospholipid found only on the inner mitochondrial membrane. Cardiolipin changes have been linked to ageing and a variety of disorders, implying that SS-31 elamipretide pre mixed peptide could have a wide range of therapeutic applications.

SS-31 has also been shown to influence BAX recruitment and activation during apoptosis [4], thereby reducing cell death and boosting cellular health. Furthermore, SS-31 Elamipretide pre mixed peptide has been shown to reduce age-related post-translational changes of heart proteins [5], suggesting its potential utility in the treatment of age-related cardiac disorders.

SS-31 elamipretide pre mixed peptide has also been demonstrated in clinical studies to improve ADP sensitivity in aged mitochondria by boosting uptake via the adenine nucleotide translocator [1]. This suggests that it has the potential to cure age-related energy decrease at the cellular level.

References:

[1] https://link.springer.com/ article/10.1007/s11357-023-00861-y

[2] https://link.springer.com/ article/10.1186/s12974-019-1627-9

[3] https://www.biorxiv.org/ content/10.1101/735001v1.abstract

[4] https://link.springer.com/ article/10.1186/s13104-021-05613-9

[5] https://link.springer.com/ article/10.1007/s11357-021-00447-6

Sequence: d-Arg-Dmt-Lys-Phe-NH2

Molecular Formula: C32H49N9O5

Molecular Weight: 639.8 g/mol

Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

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